Dr. Amit Ghosh

Dr. Amit Ghosh

Prof.
Physiology

physio_amit@aiimsbhubaneswar.edu.in

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PERSONAL INFORMATION

Dr. Amit Ghosh

Prof.

Physiology

Degree / Diploma Year of Passing Subject Name of the University/ Institution
B.Sc. Physiology Burdwan University, India
M.Sc. Physiology Burdwan University, India
Ph.D. Patho Physiology (Host-Pathogen interaction) Jadavpur University, India
  • : Research in my laboratory is focused on Cancer biology (Anticancer Drugs and molecules screening in tissue slice culture, spheroid and organoid model), Tumor biomarkers, Novel therapeutics, and Interaction of nutraceuticals with cancer. My lab is also actively involved in research on Human Genetics, Epigenetics, and Diagnostics Method development.

  • Indian Council OF Medical Research JRIndian Council OF Medical Research JRF

  • NET (National Eligibility Test), India. GATE (Graduate Aptitude Test in Engineering), India

  • Ghosh A, Saha DR, Hoque KM, Asakuna M, Yamasaki S, Koley H, Das SS, Chakrabarti MK, Pal A. Enterotoxigenicity of mature 45- kilodalton and processed 35-kilodalton forms of hemagglutinin protease purified from a cholera toxin gene-negative Vibrio cholera non-O1, non-O139 strain. Infection and Immunity. 2006 May; 74(5): 2937-46.
  • Amit Ghosh, Seakwoo Lee, Roman Dziarski, Shukti Chakravarti. 2009. A novel antimicrobial peptidoglycan recognition protein in the cornea. Invest. Ophthalmol. Vis. Sci. 2009 Sep; 50(9):4185-91.
  • Roy N, Barman S, Ghosh A, Pal A, Chakraborty K, Das SS, Saha DR, Yamasaki S, Koley H. Immunogenicity and protective efficacy of Vibrio cholerae outer membrane vesicles in rabbit model. FEMS Immunol Med Microbiol. 2010 Oct; 60(1):18-27.
  • Fadi Annaba, Zaheer Sarwar, Amit Ghosh, Seema Saksena, Ravinder K. Gill, Alip Borthakur, Gail A. Hecht, Pradeep K. Dudeja, Waddah A. Alrefai. Enteropathogenic Escherchia coli (EPEc) Inhibits Ileal Sodium-Dependent-Bile Acid Transporter ASBT. Am J Physiol Gastrointest Liver Physiol. 2012 May 15; 302(10):G1216-22.
  • Amit Ghosh, Fadi Annaba, Pooja Malhotra, Arivarasu Natarajan Anbazhagan, Pradeep K. Dudeja, Ravinder K. Gill, Waddah A. Alrefai.MicroRNA Mir-625 is a Negative Regulator of Human Apical Sodium Dependent Bile Acid Transporter (ASBT). Gastroenterology, Volume
    142, Issue 5, Supplement 1, May 2012, Page S-2.
  • Pooja Malhotra, Vinay Soni, Amit Ghosh, Seema Saksena, Ravinder K. Gill, Pradeep K. Dudeja, Waddah A. Alrefai. Proteosomal Degradation of Niemann Pick-C1-Like 1 (NPC1L1) Protein in Intestinal Epithelial Cells. Gastroenterology, Volume 142, Issue 5, Supplement 1, May 2012, Page S-132.
  • Minato Y, Ghosh A, Faulkner WJ, Lind EJ, Schesser Bartra S, Plano GV, Jarrett CO, Hinnebusch BJ, Winogrodzki J, Dibrov P, Häse CC. Na+/H+ antiport is essential for Yersinia pestis virulence. Infect Immun. 2013 Sep;81(9):3163-72.
  • Ghosh A, Mahajan PB. Can genotype determine the sports phenotype? A paradigm shift in sports medicine. J Basic Clin Physiol Pharmacol. 2016 Jun 1;27(4): 333-9. doi: 10.1515/ jbcpp-2015-0090. PMID: 26812785.
  • Mondal A, Tapader R, Chatterjee NS, Ghosh A, Sinha R, Koley H, Saha DR, Chakrabarti MK, Wai SN, Pal A. Cytotoxic and Inflammatory Responses Induced by Outer Membrane Vesicle-Associated Biologically Active Proteases from Vibrio cholerae. Infect Immun. 2016
    Apr 22;84(5):1478-90.
  • Ghosh A, Dharmarajan A, Swain PK, Das D, Verma P, Tripathy PR. Impact of Cardiovascular Factors on Pulse Wave Velocity and T otal Vascular Resistance in Different Age Group Patients with Cardiovascular Disorders. Curr Aging Sci. 2019;11(4):261-268. 11. Pramanik B, Ghosh A. Development of an Efficient, Non-Invasive Method for Cardiovascular Disease Risk Stratification in a Resource-Limited Setting. Curr Aging Sci.
    2019;12(2):91-99.
    12. Verma P, Naik S, Nanda P, Banerjee S, Naik S, Ghosh A. In Vitro Anticancer Activity of Virgin Coconut Oil and its Fractions in Liver and Oral Cancer Cells. Anticancer Agents Med Chem. 2019;19(18):2223-2230.
  • Verma P, Ghosh A, Ray M, Sarkar S. Lauric Acid Modulates Cancer-Associated microRNA Expression and Inhibits the Growth of the Cancer Cell. Anticancer Agents Med Chem. 2020;20(7):834-844.
  • Ghosh A. Breast Milk Stem Cell Survival in Neonate’s Gut, Entery into Neonate Circulation and Adaption by the Body. Curr Stem Cell Res Ther. 2020;15(2):98-101.
  • Pruseth, B., Banerjee, S., & Ghosh, A. Integration of in silico and in vitro approach to reveal the anticancer efficacy of Virgin Coconut Oil. CORD, 2020;36:1-9.
  • Pruseth B, Ghosh A, Pradhan D, Purkait S, Guttula PK. Analysis of Overexpressed miRNAin Circulation and Cancer Tissue to Develop a Potential microRNA Panel for the Diagnosis ofColorectal Cancer. Microrna. 2021;10(4):250-262. doi: 10.2174/221153661166
    6211228102644. PMID: 34963442.
  • Verma P, Mohanty N, Pruseth B, Sahoo S, Katiyar A, Singh H, Jena SK, Das RR, Som TK,Sahoo SK, Nanda P, Ghosh A. Identification of Candidate Immune System MicroRNAs Differentially Found in Colostrum and Milk Exosomes. Microrna. 2022 Jun 30. doi:
    10.2174/2211536611666220630102316. Epub ahead of print. PMID: 35786199.
  • N R S, Behera MM, Naik SK, Das SK, Gopan S, Ghosh A, Sahu RN, Patra S, Purkait S. Elevated expression of cholesterol transporter LRP-1 is crucially implicated in the pathobiology of glioblastoma. Front Neurol. 2022 Oct 4;13:1003730. doi: 10.3389/fneur.2022.1003730. PMID: 36267880; PMCID: PMC9576951.
  • Prakash S, Ghosh A, Nayek A, Kiran S. The Platelet Aggregation Inhibition Activity of Polyphenols can be mediated by 67kda Laminin Receptor: A New Therapeutic Strategy For the Treatment of Venous Thromboembolism. Cardiovasc Hematol Agents Med Chem. 2023 Feb 28. doi: 10.2174/1871525721666230228120500. Epub ahead of print. PMID: 36852811.
  • Kiran S, Patra A, Verma P, Purkait S, Chhabra G, Guttula PK, Ghosh A. Restoration of Altered Oncogenic and Tumor Suppressor microRNA Expression in Breast Cancer and Colorectal Cancer Cell using Epicatechin. Curr Mol Pharmacol. 2023;16(8):915-926. doi: 10.2174/1874467216666230210091839. PMID: 36809960.
  • Mukherjee S, Das PGS, Prakash S, Ghosh A, Priyadarshini T, Purkait S. Leukoreduction of red blood cell units decreases dysregulatory micro RNAs during routine storage: An observational study with In-silico analysis. Transfusion. 2023 Sep;63(9):1747-1757. doi: 10.1111/trf.17479. Epub 2023 Jul 10. PMID: 37427683.
  • Shaw J, Patra A, Khatun A, Ray R, Ghosh A, Mahapatra S, Panigrahi A, Bhattacharyya M. Alpha globin gene alterations modifying the phenotype of homozygous beta thalassaemia. EJHaem. 2024 May 27;5(3):440-446. doi: 10.1002/jha2.923. PMID: 38895064; PMCID: PMC11182400.

Dr. Amit Ghosh

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EXPERTISE INFORMATION
Areas of Interest
    • : Research in my laboratory is focused on Cancer biology (Anticancer Drugs and molecules screening in tissue slice culture, spheroid and organoid model), Tumor biomarkers, Novel therapeutics, and Interaction of nutraceuticals with cancer. My lab is also actively involved in research on Human Genetics, Epigenetics, and Diagnostics Method development.